Communication Dans Un Congrès Année : 2024

Fast analysis of multiple exposure speckle data to provide relative blood flow maps using Convolutional Neural Networks

Résumé

Laser Speckle Contrast Imaging is a well-established technique able to produce relative blood flow maps contactless and without using dyes. It relies on the statistical analysis of dynamic speckle images, observed when a coherent light is used to illuminate a medium that contains moving scatterers. The local speckle contrast is related to the movements of the scatterers. Multiple exposure speckle imaging (MESI) is a variant of the technique that takes advantage of multiple exposure data to retrieve more quantitative flow maps by accounting for the unwanted and superimposed contribution of static scatterers. Yet, in MESI, a model is adjusted pixelwise to the experimental data requiring long computation times and an a priori guess on the flow regimes. These issues hindered so far, the translation of MESI to clinical applications though some studies have already demonstrated its potential. Here we propose an alternative method based on Convolutional Neural Networks to analyze MESI data. The proposed CNN architecture has been trained and validated using experimental data acquired on calibrated microfluidics flow phantoms. Then, the trained network was applied to analyze MESI data acquired in vivo in mice brain. In addition to be model-bias-free, we have found that the CNN approach infers flow maps much faster than the classical pixelwise regression approach. This new approach is promising for the clinical translation of MESI.
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Recherche Data Gouv

Cite 10.57745/KHGHTO Image Pain, Frédéric; Chammas, Marc, 2023, "Multiple exposure speckle imaging contrast database obtained in vitro on microfluidic chips for various exposure, channel width, flows and optical magnification", https://doi.org/10.57745/KHGHTO, Recherche Data Gouv, V1

Dates et versions

hal-04777291 , version 1 (15-11-2024)

Identifiants

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Chao-Yueh Yu, Marc Chammas, Gurden H, Hsin-Hon Lin, Frédéric Pain. Fast analysis of multiple exposure speckle data to provide relative blood flow maps using Convolutional Neural Networks. SPie Photonics Europe, SPIE, Apr 2024, Strasbourg, France. ⟨10.1117/12.3017151⟩. ⟨hal-04777291⟩
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