The injection of a phase- and amplitude-shaped pulse into a photonic-crystal fiber provides additional degrees of freedom that can significantly influence the nature of nonlinear propagation and nonlinear and dispersive interactions. This strong sensitivity of nonlinear effects-particularly the Raman soliton self-frequency shift-greatly extends the parameter space available to generate tailored output fields for applications such as microscopic imaging. By numerical simulations, we identify the relevant interpulse interactions, and we experimentally demonstrate the additional capabilities of this nonlinear pulse-shaping method.