Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling
Résumé
Highlights d Netrin-1 is upregulated in metastatic pancreatic cancer d Hepatic stellate cell-secreted retinoic acid upregulates Netrin-1 in the liver d Netrin-1 on extracellular vesicles preconditions the metastatic niche
Domaines
CancerOrigine | Fichiers éditeurs autorisés sur une archive ouverte |
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