In this paper, we propose the use of the transimpedance amplifier configuration as a simple generic circuit for electron device-based audio distortion. The goal is to take advantage of the non-linearities in the transfer curves of any device, such as diode, JFET, MOSFET, and control the level and type of harmonic distortion only through bias voltages and signal amplitude. The case of a nMOSFET is taken as a case study, revealing a rich dependence of generated harmonics on the region of operation (linear to saturation), and from weak to strong inversion. A continuous and analytical Lambert-W based model was used for simulations of harmonic distortion, which were verified through measurements.